SIMULTANEOUS SPECTROPHOTOMETRIC DETERMINATION OF RABEPRAZOLE SODIUM AND DOMPERIDONE MALEATE IN CAPSULES BY CHEMOMETRIC METHODS
نویسندگان
چکیده
منابع مشابه
Simultaneous determination of Rabeprazole sodium and Domperidone
Three simple and sensitive methods were developed for the determination of a mixture of Rabeprazole sodium RB and Domperidone DP without prior separation. The first method A, isoabsorptive point comprised of measurement the total content of the mixture at their isoabsorptive point, while the content of RB was determined by measuring the first order derivative of its spectra at 231 nm, and the c...
متن کاملSimultaneous Spectrophotometric Estimation of Rabeprazole Sodium and Domperidone Maleate in their Combined Pharmaceutical
Two simple, rapid, economical, specific, precise and accurate spectrophotometric methods have been developed for simultaneous estimation of rabeprazole sodium and domperidone maleate in their combined pharmaceutical dosage forms. Rabeprazole sodium and domperidone shows absorption maxima at 285 nm and 287 nm respectively. The first method is based on the simultaneous equations. In the simultane...
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The significant spectral overlap (Di) 0.5 = 0.5667 which is about 75.3% overlapping of the UV/Visible absorption spectra of iron (II) and copper (II) complexes necessitates chemometric assisted methods for simultaneous analysis of these ions in the pharmaceutical mixture. These metal ions were analyzed simultaneously by UV/Visible spectrophotometric method where 8-hydroxyquinoline was used as a...
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INTRODUCTION The present work aimed to develop and validate spectrophotometric methods for simultaneous estimation of rabeprazole sodium and aceclofenac in a pure and capsule dosage form. MATERIALS AND METHODS Method 1 is based on solving a simultaneous equation. Absorbances of rabeprazole sodium and aceclofenac were measured at their respective absorbance maximas (λ max) of 283 and 276 nm. M...
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The multivariate calibration method, partial least square regression (PLS) was applied for thesimultaneous spectrophotometric determination of Lidocaine (LID) and Hydrocortisone acetate(HCA) in their mixtures. The parameters of chemometric technique were optimized and theproposed method was validated with synthetic samples and applied to analyze these drugs inpharmaceutical products with good a...
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ژورنال
عنوان ژورنال: INTERNATIONAL RESEARCH JOURNAL OF PHARMACY
سال: 2013
ISSN: 2230-8407
DOI: 10.7897/2230-8407.04616